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Abstract

A REVIEW ON LIPID NANOPARTICLES AS CARRIERS FOR ENHANCING BIOAVAILABILITY OF POORLY SOLUBLE DRUGS

Ravi Kumar, Rashmi Pandey*, Saurabh Sharma, Pranjul Shrivastava, Sandip Prasad Tiwari

Faculty of Pharmacy, Kalinga University, Naya Raipur, Chhattisgarh India (492101)

ABSTRACT

Considering lipid-based nanotransporters have several advantages, such as biocompatibility, biodegradability, low toxicity, and non-immunogenicity, nanomaterials have undergone extensive research for the delivery of drugs. However, the efficacy of therapy or the effectiveness of delivering the medication are limited by the disadvantages that accompany traditional lipid-based nanocarriers as particularly inappropriate aiming for, procurement by the system of Endothelial cells in reticulum, and rapid clearance. To contribute to facilitate identify and address the causes of a variety of diseases, a number of multifunctional nanocarriers constructed from lipids have been created constructed that improve the development of pharmaceuticals in the area of the lesions. Everyone described the latest advances along with applications of nanocarriers made with lipids in this review, wrapping both traditional and intriguing operational a lipid formulation.

Keywords: Bioavailable Drug, Self-micro Emulsifying drug delivery system


[Full Text Article]