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Abstract

REVIEW ON SYNTHESIS SCHEMES OF FIRST LINE DRUGS OF ANTITUBERCULAR DRUGS

Vishal Sahu, Vishal Kushwaha, Vijay Sahu, Satyam Shukla, Imran Khan*

Adina Institute of Pharmaceutical Sciences, Sagar (M.P.)

ABSTRACT

Tuberculosis (TB) is an infectious disease caused by a variety of mycobacterium strains, the most prevalent of which being Mycobacterium tuberculosis. M. tuberculosis, M. africanum, M. bovis, and the Bacillus Calmette-Guérin strain, M. microti, M. canettii, M. caprae, M. pinnipedii, and M. mungi are all members of the M. tuberculosis complex. Other than M. tuberculosis complex, other species (M. avium complex, M. gordonae, M. kansasii, M. simiae, M. chelonae, M. fortuitum, etc.) do not cause tuberculosis in humans. TB mainly affects the lungs but can also affect other regions of the body. For many years, it was thought to be a poverty disease due to its rarity in developed countries. The present review focus on some synthesis schemes of first line drugs of antitubercular drugs.

Keywords: Antitubercular, Synthesis Schemes, Review


[Full Text Article]